ICSI / Male Factor Infertility


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Intracytoplasmic Sperm Injection (ICSI)

The ICSI procedure is primarily performed for those couples who experience male factor infertility or have had unexplained infertility.   It is now commonly performed as part of the IVF protocol for many patients and essentially neutralizes male factor infertility by normalizing fertilization with IVF.

ICSI is done in the IVF laboratory by highly skilled embryologists following the egg retrieval.

  • The male partner provides a semen sample.
  • A single sperm is selected under high magnification and injected into the egg using a high performance microscope and specialized equipment.
  • The now fertilized egg is observed by the embryologists for embryo growth and development
  • After the embryologists determine the embryo is developing normally, it will then be implanted into the uterus.


Male Factor Infertility

This type of infertility can be caused by one of the following factors:

  • An absence of sperm in the ejaculate
  • Poor sperm motility
  • Low sperm count
  • Abnormal sperm shape
  • Sperm that has in a prior IVF cycle been unable to penetrate the egg

According to The American Society of Reproductive Medicine, male factor infertility is responsible for about 30% of infertility cases and can contribute infertility to an additional 20% of cases. Please click here to watch an outstanding video about male infertility. The video discusses male infertility including possible causes, diagnostic testing, and treatments.